Vet Dermatol 2019;30(2):87-90. Six adult horses with a mean weight of 528 kg were . We recommend Platinum Skin and Allergy or Aleira. 5. Dosage options starting at $0.25 per dose. Excitement rather than lethargy can occur occasionally, especially in cats. Your Price: $2.20. Although no studies of pharmacokinetics in cats have been published, oclacitinib is well tolerated and seems to be safe when used in cats at 1 or 2 mg/kg q12h for 28 days.21 Further studies are needed to investigate adverse effects associated with long-term use in cats. In the past 5 years, however, oclacitinib (Apoquel; zoetisus.com), a Janus kinase (JAK) inhibitor, has become another important drug in the management of allergic pruritus. 28. Horse dosing is 5 pills. 2. These are known as allergy shots. Her asthma had gotten so bad I thought I wouldnt be able to ride her again, but now we are back to w-t-c. She is down to every other day. Apoquel starts working within 4 hours of administering the first dose and controls itching within 24 hours. This drug has been used in dogs with some pretty fabulous results. While this is a very important strategy for some types of Equine Asthma ("classic" RAO), it may not be as important when managing those with Summer-Pasture-Associated disease. These might include antihistamines such as cetirizine, which you can buy over the counter as Zyrtec from any drug store or pharmacy, or hydroxyzine, which requires a veterinary prescription. 405 HERON DRIVE SUITE 200 SWEDESBORO, NJ 08085-1749 | 2004-2023 WEDGEWOOD PHARMACY, ALL RIGHTS RESERVED. Breeding and Reproduction Horse breeding from planning through foal care; Diseases and Conditions Horse-health-problem risk factors, prevention, diagnosis, and treatment; Farm and Barn . Pre-slaughter withdrawal time is 14 days following the last dose. Cyclosporine, which is approved for the treatment of canine atopic dermatitis, has an onset of efficacy of up to 4 weeks. We can let your veterinarian know that you are interested in our compounded Dexamethasone. The Horsesexperts answer your questions during a monthly live audio event. Diphenhydramine can alter the results of skin allergy testing; discontinue this medication at least 2 weeks before testing. Frank RK, Galvan BA, Schoell AR, et al. Pollen and other plant-based aeroallergens are the source of their distress, and they fare much better inside, Many allergens can cause skin reactions. Search term . New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Some allergic reactions are unexpected, as White has realized through his research. J Vet Pharmacol Ther 2014;37(4):317-324. With equine allergies, prevention is a horse owners best bet. Depending on the size of a cat and the condition being treated, a veterinarian may elect to alter the dosage. If the patient remains stable and other controlling measures-such as allergen avoidance, allergen immunotherapy, and preventive topical therapyhave been implemented, the use of oclacitinib can be limited to flare control.16, Although oclacitinib is licensed for use in dogs, it has been reported to be effective to treat pruritus in allergic diseases in other species, including cats.17-20 shutterstock.com/Thrithot, Although oclacitinib is licensed for use in dogs, it has been reported to be effective to treat pruritus in allergic diseases in other species, including cats.17-20. 22. After that it would be about $250 every 6 weeks or so if I cant further reduce time between pills. 8. 17. Hay naturally contains microscopic fungal spores, plus bacterial and dust components that horses inhale as they eat, explains Lisa Fultz, DVM, MS, Dipl. In this study, 70% of the study population receiving oclacitinib showed improvement in pruritus compared with 75% in a group receiving methylprednisolone.18 Based on this study, a higher dose with a longer induction period seems to be the key to successfully treating feline pruritus with oclacitinib. 21. Rabies in Animals. If you struggle to get your dog to take tablets, you can try hiding it in their food, or wrapping it in a tasty piece of meat. The American company "Zoetis Inc" created the drug Apoquel, which deservedly occupies a leading position among drugs for eliminating itching in dogs, regardless of its etiology. Therefore, in many of these cases, veterinarians use steroids sparingly, says Fultz, at lower doses than recommended, or they turn to non-steroidal medications. 29. After completing a doctorate thesis and a rotating internship at the University of Zurich, Switzerland, he moved to the United States, where he completed a 3-year veterinary dermatology residency at the University of Georgia in 2004. Apoquel is sold per tablet in strengths of 3.6 mg, 5.4 mg, or 16 mg. The dosage will depends on your dog's weight. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. Gadeyne et al compared prednisolone and oclacitinib at recommended doses and found that both drugs resulted in similar rapid effects with regard to pruritus and dermatitis reduction.11 Little et al compared oclacitinib to cyclosporine. Pruritus is a common clinical sign in allergic skin diseases. Yamaoka K, Saharinen P, Pesu M, et al. This is a new treatment option, and currently the tablets are not FDA approved for horses, only dogs. So lets review why allergies happen, how they affect your horses body, and how to treat themor, better yet, how to avoid them altogether. Many of these cytokines bind to cytokine receptors that have JAK enzymes associated with their cytoplasmic portion. If your horse's test results (from a BAL or tracheal wash) show a certain cell type in the lungs, we may recommend trying Zyrtec!Clenbuterol: This is a bronchodilator that may be beneficial in treating some horses with Equine Asthma. Recently, researchers have delved into the causes and consequences of what now falls under the umbrella term equine asthma. Apoquel tablets are scored to be halved to ensure that the ingredients are equally distributed. Give one chewable per month to the dog. Vercelli A, Cornegliani L. Use of oclacitinib in treatment of canine idiopathic ear tip vasculitis. A blinded, randomized clinical trial comparing the efficacy and safety of oclacitinib and ciclosporin for the control of atopic dermatitis in client-owned dogs. This product is a hand-held device that administers an anti-inflammatory mist into the horses nostril. If she stays the way she is now, I will play with spacing it out furtherfirst with every 2 days. Before your vet administers immunotherapy, though, you must identify your horses respiratory and skin allergies. The most common side effect is lethargy, dry mouth, and urinary retention. Apoquel is a non-hormonal drug for dogs, used for dermatitis of various etiologies, which are accompanied by itching. Ortalda C, Noli C, Colombo S, et al. Oclacitinib was well tolerated in both studies. 16. The only FDA-approved equine PSGAG. Nobody wants to be itchy and constantly scratching. If your horses allergies are seasonal, talk to your veterinarian about steps you can take to stay ahead of them. She still has her mane this year- which is good! It definitely makes them more comfortable. Successful treatment of atopic dermatitis with the JAK1 inhibitor oclacitinib. In fact, in our recent study evaluating almost 400 potential allergens, latex proteins were the most significant allergens for diagnosing severe equine asthma.. Vet Dermatol 2013;24:48-e12. In the first pilot study, oclacitinib (0.4 to 0.6 mg/kg, q12h for 14 days, then q24h for 14 days) was used to treat pruritus in cats with non-flea, nonfood-induced hypersensitivity dermatitis. Gonzales AJ, Bowman JW, Fici GJ, et al. At that point, the treatment can be changed to oclacitinib. Drake GJ, Nuttall T, Lpez J, et al. Initially, the recommended dose of 0.4 to 0.6 mg/kg should be given twice daily for up to 14 days. Join us as we interview leading equine researchers from the University of Kentucky, Problem Solver Series: How to Control Nuisance Birds on Horse Properties. Gonzales AJ, Humphrey WR, Messamore JE, et al. Feline idiopathic ulcerative dermatosis treated successfully with oclacitinib. Use of them does not imply any affiliation with or endorsement by them. Even though the drug is currently labeled for use in dogs (with allergic dermatitis), initial studies show that horses absorb it well, Fultz says. Equine Asthma- yep, that's the new name for "heaves," "RAO," "COPD" or whatever else we've called it over the years! The pharmacokinetics of oclacitinib maleate, a Janus kinase inhibitor, in the dog. Yes, we looked into this approach, but unfortunately it was not a viable option for my horse for a variety of reasons including other health factors and severity of allergies. Stay current with the latest techniques and information sign up below to start your FREE Todays Veterinary Practice subscription today. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Apoquel comes in tablet form only. These can be severe and lead to a life-threatening, airway-blocking, whole-body reaction called anaphylaxis. Unlike some other allergy. This content is intended for counseling purposes only. Comparing Apoquel and Cytopoint. Apoquel can be administered to dogs over the age of 12 months for 14 days, during which the veterinarian would most likely decrease the dose to once a day. On the topic of simple and economical allergy management, a readily accessible ingredient that helps many horses is, Recently, we have found that latex, which is everywhere in the horses environmentembedded in riding surfaces and racetracks, for examplemay be associated with severe equine asthma, he says. The Feed: One of the most common recommendations for managing Equine Asthma has always been to stop feeding hay. U.S. Food and Drug Administration Center for Veterinary Medicine 7500 Standish Place Rockville, MD 20855 www.fda.gov . While efficacy was comparable to that observed in the previous studies, significant positive effects on the dogs quality of life were observed in >91.5% of cases after 630 days. For atopic and allergic dermatitis, Apoquel may be given to dogs at a dosage of 0.18 - 0.27 mg/lb. Helpful steps you can take include providing full-body fly apparel, applying fly spray liberally, avoiding turnout at dusk and dawn, and using fans in stalls to disrupt insect flying patterns. Treatment will probably need to repeated somewhere between 1 and 6 weeks after the initial treatment course. Unlike steroids, the drug has minimal impact on the immune system. Then reintroduce each, one by one, while monitoring for hives or other signs of allergies. The tablets come in three dose sizes: 3.6mg 5.4mg 16mg Always give the dose prescribed by your veterinarian. Oclacitinib maleate is used twice daily for two weeks and then dropped to a maintenance dose of once daily. Im not dealing with food allergies but both the company and the vet did not recommend allergy shots for my mare. Speak to yourveterinarian in an emergency. Saridomichelakis MN, Olivry T. An update on the treatment of canine atopic dermatitis. Vet Dermatol 2017;28(5):512-e123. Cost is <$50/month, its easy, and its usually very effective. @vxf111 we were told the same thing for food allergiesthat they did not make serums fot them because they were not very effecttive and the the expectation was that the allergen be removed from the diet. Use of oclacitinib (Apoquel; Zoetis) for treatment of cutaneous mastocytosis in a cat. Allergies are generally managed based on the severity of clinical signs. The anti-inflammatory effects of dexamethasone are about twenty-five times stronger than those of natural cortisol. Successful treatment of atopic dermatitis with the JAK1 inhibitor oclacitinib. This study showed that pruritus was improved in only 42% of the study population; thus, use of oclacitinib in cats did not seem to be as effective as in dogs.17 A follow-up study was conducted with a higher dose (0.7 to 1.2 mg/kg) and a longer induction period (28 days). The recommended dosage of Apoquel 3.6mg tablets is 0.18 to 0.27 milligrams per pound of body weight. A blinded, randomized, placebo-controlled trial of the safety of oclacitinib in cats. 10. Apoquel is a dog allergy medicine used to treat and control chronic manifestations of allergic and atopic dermatitis in dogs. 3. Lopes NL, Campos DR, Machado MA, et al. Transdermal applicator that gives easy & accurate dosing every time. APOQUEL FOR DOGS DOSE. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Old fashioned drugs like Benadryl and steroids don't work well any more. Dosage Chart She reports choosing Apoquel over corticosteroids in several of her allergic patients that are also at risk for developing laminitis. Pulsoni D, Freire A, Ferreira DR. Juvenile-onset ischemic dermatopathy in two dogs treated with oclacitinib. This links to a pdf file Storage and Handling : Store at controlled room temperature 20 to 25C (68 . In the past 5 years, however, oclacitinib (Apoquel; ), a Janus kinase (JAK) inhibitor, has become another important drug in the management of allergic pruritus. Therefore, it is important to get your veterinarian involved right away. Apoquel should be administered orally, twice daily for up to 14 days, and then once daily for maintenance therapy. We have been using an inflatable fleece e-collar on her . 1,2 For over 30 years, Adequan i.m. Luckily most of her allergies appear to be insect-based and she responds very well to the serum for that. On the label for dogs, Apoquel is used every 12 hours for the first 14 days of use, then backed down to dosing every 24 hours once a day. The purpose of Apoquel 16mg Tablets for dogs is to alleviate itching related to allergic dermatitis and address the signs of atopic dermatitis. Little PR, King VL, Davis KR, et al. 13. Specifically, studies in cats have used the following dosage: Initially, doses ranging from 0.4 to 1.2 mg/kg body weight, twice daily, for 24-28 days. Haugh IM, Watson IT, Menter MA. These inhaled substances can trigger an allergic response that causes narrowing of the airways, mucous secretion, and cough., Luckily, minimizing common allergens in your horses environment could suffice to restore his comfort and breathing. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. Oclacitinib is available in 3 different tablet sizes: 3.6, 5.4, and 16 mg. Olivry T, Banovic F. Treatment of canine atopic dermatitis: time to revise our strategy? Look for a supplement with at least 1,500mg of DHA per serving. Rectal Prolapse in Dogs and Cats. Allergies can develop at any time, in any horse, and seemingly for any reason. Its an annoying pill schedule to keep track of, but my boarding barn has been great about it. Oclacitinib is available in 3 different tablet sizes: 3.6, 5.4, and 16 mg. But it will take me through a month if I stay at every other after the loading. Most horses in our area of North Carolina are "Summer-Pasture-Associated" asthma patients, so we recommend starting yearly treatment or management in March or April. Interestingly, the results suggest that oclacitinib has immunosuppressive properties, but only at a higher dosage than that approved on the label. 1800PetMeds is your online pet store offering discount prices on pet supplies, medications, vitamins and supplements for your pet. Acupuncture: It appears that some horses with Equine Asthma can benefit from acupuncture to help with breathing function. This treatment is typically effective, but the steroid is still absorbed into the body, which can result in laminitis risk, similar to Option 1. Recently, one group has looked into immunomodulatory properties of oclacitinib by observing canine T-cell proliferation and cytokine productions in vitro. Copyright 2023 Today's Veterinary Practice Web DesignbyPHOS Creative. Weve also been able to start rehabbing back into work. 30. Milder cases of asthma are still associated with coughing, airway inflammation, mucous production, and poor performance.. Dexamethasone: EZ Dose Micro Transdermal Gel, Dexamethasone: Twist-a-Dose Transdermal Gel, Discussion Guide for Pet Owners and Veterinarians, Medication Information for Pet and Horse Owners. Apoquel Dosage in Dogs Apoquel tablets for dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet. I havent noticed any abnormal side effects. Shes on 5 pills once a day for 7 days, after that we will drop to every other day, and then see how far we can space it out. Once you have the horse's symptoms under control, you can try re-introducing hay. Many allergic reactions are evident as a mild case of transient hives. There are two types of this condition, summer-pasture-associated and classic recurrent airway obstruction (RAO). Posted by Lucile Vigouroux | May 4, 2022 | Article, Diseases and Conditions, Farm and Barn, Hives & Skin Allergies, Horse Care, Medications, Nutrition, Seasonal Care, Skin Problems. Pros and cons of oclacitinib therapy. Vet Dermatol 2015;26(1):23-30, e7-8. In atopic dermatitis, it is mainly mediated by a large group of proinflammatory and proallergic Th2 cytokines (e.g., interleukin [IL]-4, IL-5, IL-10, IL-13, IL-31). Oclacitinib (APOQUEL) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. 23. So I want to make sure she has the support she needs to acclimate to hot humid summer weather. 6. Saridomichelakis MN, Olivry T. An update on the treatment of canine atopic dermatitis. Binding of these cytokines to their receptors activates the JAK-STAT (signal transducers and activators of transcription) pathway, which leads to further cytokine production.1 In recent studies, IL-31 has been shown to play an important role in pruritus, and elevated serum levels of IL-31 have been found in many atopic dogs.2, There are 4 JAK families in mammals: JAK1, JAK2, JAK3, and TYK2. Oclacitinib preferably inhibits JAK1 and, to a lesser degree, JAK3, resulting in decreased activity of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31).4. Since oclacitinib is a rather weak anti-inflammatory drug, it was suggested that remission of active moderate to severe atopic dermatitis be induced with a course of a broad inflammation-targeting drug, such as a short-acting glucocorticoid, until clinical signs become mild. With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program. 9. Since it became available in 2014, several clinical studies have confirmed its antipruritic effect not only in dogs but also in cats, as well as in other immune-mediated diseases. Several of their drugs are eligible. 2. The recommended Apoquel (main ingredient, oclacitinib) dosage for dog use is as follows: The recommended dosage is 0.18 to 0.27 mg of oclacitinib per pound of body weight, for the first 14 days. However, a small subcategory of asthmatic horses suffer from pasture-associated equine asthma. Speak to yourveterinarian in an emergency. Many allergens can cause skin reactions. A newer prescription drug, Apoquel (oclacitinib) has recently hit the market and might prove useful for allergic horses. Thereafter the dose should be reduced to once daily for maintenance. Fultz adds that over time this process teaches the immune system to tolerate exposure to substances it previously considered irritating. Its anti-inflammatory and expectorant properties can soothe irritated lung tissues and help to expel mucus.Licorice root should not be fed to pregnant mares. Webcast | But Im not sure how much the long term cost will be yet. It's typically prescribed twice daily for up to 14 days and then once daily after that. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. DERM DIALOGUE. 15. Because many respiratory allergies come from the dust in hay and bedding, veterinarians generally recommend maximizing fresh-air time through turnout. A horse can hypothetically be allergic to anything he touches, inhales, ingests, or has applied to or injected into his body. Typically, a few sessions are required. Aymeric E, Bensignor E. A case of presumed autoimmune subepidermal blistering dermatosis treated with oclacitinib. 17. She is a New-York-based freelance author with a passion for equine health and veterinary care. Skip to Article Content; Skip to Article Information; Search within. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. Weve been doing really well with every other day dosing. Proc (Bayl Univ Med Cent) 2018;31(4):524-525. Maximizing ventilation when horses are stalled and bedding with low-dust options such as wood byproducts; Purchasing dust- or mold-free hay and wetting, soaking, or steaming it prior to feeding to reduce inhaled particles; and Offering an alternative feed than hay for low-dust options. Haugh IM, Watson IT, Menter MA. Dr. Nao Hensel obtained her doctor of veterinary medicine degree from Colorado State University in 2010. 24. Immunotherapy, also called hyposensitization therapy, is a strategy used to gain allergen-specific immune tolerance, says Fultz. Do not use in breeding, pregnant, or lactating dogs. To overcome its delayed effect, cyclosporine is often initially combined with other drugs such as prednisolone to accelerate the anti-inflammatory and antipruritic effects. To overcome its delayed effect, cyclosporine is often initially combined with other drugs such as prednisolone to accelerate the anti-inflammatory and antipruritic effects. Treatment success in three Andean bears (Tremarctos ornatus) with alopecia syndrome using Oclacitinib maleate (Apoquel). When working with a liquid: Multiply your horse's weight in pounds times the dose rate in milligrams per pound. Uses for Apoquel Apoquel is the #1 prescribed medicine for fast, effective relief of allergic itch and inflammation due to atopic and allergic dermatitis 1 Indications Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. The onset of efficacy for oclacitinib is up to 1 week, but Little et al found that after 4 weeks of treatment, both drugs demonstrated comparable control of clinical signs. Simpson AC, Schissler JR, Rosychuk RAW, et al. That's why dosage is usually tapered down to the lowest effective dose. For more information, please see the full Prescribing Information. Lopes NL, Campos DR, Machado MA, et al. Designed by Elegant Themes | Powered by WordPress, You need to be logged in to fill out this form. Vet Dermatol 2016;27(Suppl 1):100 (abstract). More severe ones, however, can truly take a toll on your horses health and make him miserable. If you must give corticosteroids to an asthmatic horse, your veterinarian might prescribe them to be administered via an aerosol route through the nostril (rather than orally or via injection), which minimizes the amount that gets into the general circulation. That was 5-6 years ago now. J Zoo Wildl Med 2017;48(3):818-828. Lucile Vigouroux holds a masters degree in Equine Performance, Health, and Welfare from Nottingham Trent University (UK) and an equine veterinary assistant certification from AAEVT. She then completed a 1-year rotating small animal internship in Massachusetts followed by a 3-year veterinary dermatology residency in Georgia. 8. While efficacy was comparable to that observed in the previous studies, significant positive effects on the dogs quality of life were observed in >91.5% of cases after 630 days. Since oclacitinib has been shown to be comparable to prednisolone, oclacitinib can be a good alternative to prednisolone when combined with cyclosporine for initial treatment. Log in to fill, refill or renew the medication prescribed by your veterinarian. Zyrtec: The human antihistamine may be beneficial in a small proportion of horses with Equine Asthma. For this first stretch, thats not going to get me too far since I need the loading dose up front. She would be a scratching mess without it. Therefore, the recommended initial dosage for dogs 6.6-9.9 lbs is of a 3.6 mg tablet twice daily. Oclacitinib in feline nonflea-, nonfood-induced hypersensitivity dermatitis: results of a small prospective pilot study of client-owned cats. Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. The dose of Apoquel tablets is 0.18-0.27 mg/lb (0.4-0.6 mg/kg). Atopic dermatitis is often a complex disease that requires a multifaceted approach. Topical suspension administered in the ear. Equine Nutrition FAQ Series, sponsored by Purina Animal Nutrition. The powerful network of cells and antibodies known as the immune system can recognize dangerous invaders and disarm them before they hurt the host. Your veterinarian also may use dexamethasone in high doses in emergencies for anaphylactic reactions, spinal cord trauma or shock. I draw up a little calendar for them each month to help keep track. J Vet Pharmacol Ther 2014;37(3):279-285. Each dosage is sold per tablet, in 20 count, or 100 count bottles. For example: 1,000 lb horse X 10 mg/lb = 10,000 mg. to 14 days, and then administered once daily for maintenance therapy. I have not tried to go less than that. View more. When your dog is itchy, you get desperate to make him feel more comfortable. Works on all common sources of allergens. All rights reserved. This might, down the road, be an easier and less expensive alternative for horse owners. Fukuyama T, Ganchingco JR, Bumer W. Demonstration of rebound phenomenon following abrupt withdrawal of the JAK1 inhibitor oclacitinib. Allergen avoidance and allergen-specific immunotherapy are measures that address the allergy itself; various drugs are available for symptomatic management. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Oclacitinib in feline nonflea-, nonfood-induced hypersensitivity dermatitis: results of a small prospective pilot study of client-owned cats. Levy BJ, Linder KE, Olivry T. The role of oclacitinib in the management of ischaemic dermatopathy in four dogs. Ortalda C, Noli C, Colombo S, et al. My mare started on 5 pills every day and then we were able to move her down to 5 pills every other day. The dose range is very strict, I do not recommend going above the recommended dose due to immune suppression, below the range and it doesn't seem to work in most cases. This is interesting. Powered by Discourse, best viewed with JavaScript enabled. Trials showed that spreading out dosing was more successful than lowering. However, the study showed that cyclosporine caused a 3-fold higher risk for developing gastrointestinal side effects (vomiting and diarrhea) compared with oclacitinib.12, Despite its delayed effects, cyclosporine is still a popular drug to treat canine atopic dermatitis because in some cases it can be dosed every other day or even every third day after initial daily treatment. As a result, muscles relax and cause heavy sedation, notes DailyMed. Vercelli A, Cornegliani L. Use of oclacitinib in treatment of canine idiopathic ear tip vasculitis. I know there are some cases where the horse only needs 5 pills 1x a weekothers where its every 4 days.My vet did say she has one client whos horse has gone down to 2 pills every 3 days. Dosing Chart Warnings I often recommend switching your Asthma horse off of regular hay and trying a period of hay-replacement to see if it helps. Bursatti, Leeches) in Dogs, Cats and Horses. $ 78.30 - $ 245.00. Olivry T, Banovic F. Treatment of canine atopic dermatitis: time to revise our strategy? Stay up-to-date on the latest news about your horse's health with FREE newsletters from TheHorse.com. I have noticed that in general she is more comfortable on cooler days. This medication may be a very good option for minis, since the costs will be much lower. Cochet Faivre N, Degorce-Rubiales F. Clinical eosinophilic popular dermatitis associated with histological eosinophilic granuloma rapidly responsive to oclacitinib in an adult Labrador retriever.