in shops or devil rooms), The only way to survive the falling sword is either through extra lives, by using items that would make you invincible, such as Gnawed Leaf or playing as The Lost. Re-rolled items pick from the current room's item pool. Hook Worm, Wiggle Worm etc. Unlocked from the 'U broke it!' Counts as 1 of 3 spider items needed towards the Spider Baby transformation. Counts as 1 of 3 familiar items needed towards the Conjoined transformation. This includes key blocks and secret room doors, +1.0 Damage Up, but each rock tear has a random damage modifier that can go up or down (x0.5 to x2), Allows Isaac to charge by double tapping the same direction, dealing damage to any enemies caught, You are invincible while charging (doesn't include self-damage like Blood Donation machines), The dash deals x4 your current tear damage + 8, Doesn't have to be in a straight line, you can hold another button to curve it, Has a 3 second cooldown before it can be used again, While not moving your speed rapidly increases up to a bonus of +0.5, While you have this +0.5 bonus, moving will cause Isaac to fart around the room, spawning poison gas clouds, The farts stop spawning once you reach your regular movement speed, Poison deals damage equal to half your tears per tick, Isaac is immune to Poison from enemies, such as Gasbag, Gives you a wide circle halo which grants 7 orbital tears upon entering a new room, The tears orbit for 13 seconds before dropping off, Has a chance to absorb any enemy tears and add them to the orbiting tears. Stat options are: +1.0 Damage, +0.6 Tears, +0.2 Speed, +5.25 Range, Also drops either a bomb, a key or 3 coins on the ground. ?s soul, blue baby's soul, blue babys soul, When you kill an enemy, you have a chance to get +0.5 damage up for the current room, UNLOCK: Unlock this item by beating the Dark Room with Samson, *, hair, pony, tail, brown, red, samsons lock, Gives a 25% chance to reveal map icons at the start of a new floor (The same effect as the Compass), UNLOCK: Unlock this item by beating the Chest with Cain, When you kill an enemy, you have a chance to spawn a transparent Dead Bird familiar, The Dead Bird familiar deals 2 damage per tick to enemies while in contact with them, UNLOCK: Unlock this item by beating the Isaac boss with Eve, *, grey, gray, black, striped, eves bird foot, REPENTANCE - No longer replaces chests that have already spawned, UNLOCK: Unlock this item by beating Ultra Pride, * northernlion, drop the left hand, paw, bloody, bleeding, grey, gray, While held, tinted rocks and rocks with a crawlspace below them will flash white every 10 seconds, *, grey, gray, silver, lump, metal, stone, Turns all troll bombs into bombs which you can pick up and use, Super Troll bombs turn into 1+1 free double bomb pickups, Gives your tears a random worm effect every few seconds, The possible tear effects include: Whip Worm, Ring Worm, Wiggle Worm, Flat Worm, Hook Worm, Pulse Worm, Tape Worm and Lazy Worm, While held, Tape Worm doubles your range stat and halves your tear height stat, Every time you get hit, you have a chance to activate the D6, D20, D8, D10 or D12 effect. This spawns friendly charger enemies and causes Isaac to deal 5 contact damage (same as the shade did). Explosions now only heal Isaac for half of a heart (previously healed a full heart), * item room, treasure room, item room pool, fire, heart, orange, burning, stannis, Makes tears break into 4 smaller tears on impact with anything, which deal half of your damage, * item room, treasure room, item room pool, brown, orange, headless, crickets body, When getting hit, this item has a chance to drop a soul heart or black heart, The chance to spawn a heart is affected by your luck stat and at +22 Luck it will activate 50% of the time, Enemies have a chance to drop half a red heart when killed, Item Pool: Item Room, Devil Room, Curse Room, Demon Beggar, * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool devil pool, devil room pool, devil deal, item room, treasure room, item room pool, gimp mask, the lost item pool, grey, gray, black, An item only found in the secret room pool, * secret room pool, , the lost item pool, purple, black, grey, gray, flower, mtg magic the gathering, vintage, When you take damage, 1-2 coins will drop on the floor, When playing as the Keeper, this item drops 0-1 coins instead, * shop room pool, shop item pool, item room, treasure room, item room pool, pink, oink, Isaac's tears have a 15% chance of causing a fear effect, Feared enemies will run away from Isaac temporarily, The chance to fear enemies is affected by your luck stat and at +85 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, While at full red health you also shoot a projectile across the room with each swing, dealing your current Damage + 2 (similar to the Master Sword in Zelda), UNLOCK: Unlock this item by defeating challenge #39 (Isaac's Awakening), While held, a red outline of a door will appear on certain walls. Deflected tears turn into homing tears and fire back at enemies, dealing 2 damage. Both charge at the same time and using Anima Sola chains both in the same spot, Significantly increases damage by +21.6, however the damage boost wears off slowly over time at a rate of roughly -0.04 per second, Every enemy you kill adds +0.02 Damage to the timed effect of Red Stew, UNLOCK: Unlock this item by defeating Satan as Jacob & Esau, When used, removes all your passive items and teleports you to Isaac's Bedroom, For every passive item removed, you are given a choice of 3 random pedestal items from any item pool. UNLOCK: Unlock this item by beating the Boss Rush with Azazel, * devil pool, devil room pool, devil deal, grey, gray, bloody, Spawns a trapdoor at Isaac's feet which allows him to travel to the next floor, Digging in certain spots with objects or markings on the floor will guarantee a crawlspace once per floor, In Sheol, Cathedral, Chest and Dark Room this item either opens a Crawl Space, or does nothing, Cannot spawn a trapdoor directly infront of a secret room entrance, Can destroy rocks if used when Isaac is flying over a rock, * secret room pool, devil pool, devil room pool, devil deal, silver, grey, gray, dig, spade, shovel, Counts as 1 of 3 astrology items needed in the same run to unlock Planetariums, * shop room pool, shop item pool, item room, treasure room, item room pool, brown, pink, When used, spawns a Monstro which will jump on a random enemy in the room, dealing 120 damage and destroying nearby obstacles, UNLOCK: Unlock this item by beating the Basement II for the first time, * item room, treasure room, item room pool, white, grey, gray, bloody, monstros tooth, monstro tooth, Everytime you fire a tear, there is a chance that you will also fire three more tears in all cardinal directions, The chance to fire 4-way tears is affected by your luck stat and at +15 Luck it will activate every time, At +0 luck the effect has a 30% chance to activate, UNLOCK: Unlock this item by beating Lokii for the first time, * item room, treasure room, item room pool, grey, gray, devil, lokis horns loki horns, A familiar that follows Isaac and charges forwards, dealing 3.5 damage per tick to any enemies it comes into contact with, REPENTANCE - The damage tick rate on Little Chubby has been increased, UNLOCK: Unlock this item by beating the Caves II for the first time, * item room, treasure room, item room pool, yellow, smile, face, bug, Tears now have a chance of slowing enemies and their projectiles for 2.5 seconds, The chance to slow enemies is affected by your luck stat and at +15 Luck it will activate every time, * item room, treasure room, item room pool, black, grey, gray, red, bug, Has a chance to drop when exploding a tinted rock, UNLOCK: Unlock this item by destroying 100 tinted rocks, * tinted rock, marked rock, grey, gray, lump, white, Reveals adjacent rooms up to 2 rooms away, this includes revealing if you're next to a Secret Room or Super Secret Rooms, Gives Isaac a slight glow when Curse of Darkness is active, Blocks damage from projectiles falling from above, * item room, treasure room, item room pool, spelunky, miner, mining, helpmet, light, purple, olmec yama Based on the Steam Workshop mod created by Eufuu, UNLOCK: Unlock this trinket by having a lot of blue flies at once, While held this trinket gives your familiars homing shots, Added as part of the Afterbirth+ Booster Pack #5. UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted ??? The angel room spawned by The Stairway item also counts, Giving money to a beggar gives a flame orbital, UNLOCK: Unlock this trinket by defeating Mother as Tainted Bethany, Upon entering each new room, this trinket has a chance to copy one of your current familiars, If you have no familiars instead it will spawn either Brother Bobby or Sister Maggy, UNLOCK: Unlock this trinket by defeating Isaac, ?? The Forgotten - Your Soul is now unchained and free to move. Holding down the fire button again will quickly release all stored teared, The charge time and max tears stored scales with your current tears stat, Greatly reduce Isaac's size, to an extent where some enemy tears will now travel straight over him without dealing damage if they are high off the ground. It will hunt down other enemies, dealing contact damage which scales with your tear damage, After 5 seconds the red soul explodes (Isaac doesn't take damage from this effect), UNLOCK: Unlock this item by defeating The Beast as The Lost, *, this item is irrelevant 99.94% of you wont kill the beast as the lost me included :(, When used, gives you number of blue flame orbitals based on the number shown over this item, It starts at 1, and increments each activation, giving you more familiars each time you use it, The flames fire tears at the same time Isaac does, that deal a flat 3 damage, If a flame touches an enemy, it deals contact damage equal to double your current tear damage and then disappears, You can have a maximum of 24 flame orbitals at once, Each flame has a chance to spawn as one of many variants, such as green flames that poison enemies, or a crucifix flame that spawns a random horseman familiar + Locusts when it is extinguished, UNLOCK: Unlock this item by defeating The Beast as Bethany, Soul hearts give you small permanent stat increases when picked up, Possible stats include +0.3 Range Up, +0.2 Luck Up, +0.2 Damage Up, +0.1 Tears Up, +0.04 Speed Up, UNLOCK: Unlock this item by defeating Greed Mode as Bethany, Spawns a random charmed enemy which fights by your side and copies your exact movements, similar to how Jacob & Esau work, The familiars fire tears at the same time as Isaac, and have a visible health bar showing how much damage they can take before dying, UNLOCK: Unlock this item by defeating The Beast as Jacob & Esau, You respawn as a tiny version of Isaac, with a greatly reduced hitbox and +0.2 Speed Up, When the effect activates you deal 35 damage to nearby enemies, Once unlocked, if you have already unlocked the tainted version of the character you're playing as, Inner Child is guaranteed to spawn in the hidden closet on the Home floor, UNLOCK: Unlock this item by defeating Greed Mode as Jacob & Esau, Item pedestals now cycle between 5 random items, UNLOCK: Unlock this item by defeating The Beast as Tainted Isaac, Enemies that touch Isaac will now bounce off him and fly off in the opposite direction, Bounced enemies will take 10 damage if they slam into the wall, This item also gives a random chance for enemy shots to bounce off you without taking damage, UNLOCK: Unlock this item by defeating The Beast as Tainted Magdalene, 33% chance to reroll items with a quality of 2, Quality is a hidden mechanic in Repetance for all items and ranges from 0-4. Can cause white poops through other item effects such as A Card Against Humanity or Re-Lax pills. Smaller enemies spawn 2-3 tears, and bosses spawn a maximum of 16, Tears from this effect maintain tear modifiers and status effects that Isaac currently has, Isaac doesn't take damage from the tears created by this item, Every time you take damage, a tiny Isaac familiar will spawn, which follows you and shoots tears at nearby enemies that deal 1.3 Damage, The mini-Isaacs stay with you between floors, but can die if they take too much damage, Maximum number of mini-Isaacs is 16 at one time, Mini-Isaac's keep some of the abilities and appearance that Isaac has - e.g. ?, Satan and The Lamb as Tainted Apollyon, Gives you a red attack fly, that will charge at enemies in the same direction you are shooting, Deals damage equal to your current tear damage, Stops charging once it hits an enemy and returns to Isaac's side, UNLOCK: Unlock this trinket by defeating Mother as Tainted Apollyon, Gives a 33% chance to spawn an extra blind pedestal item in all future item rooms. By selecting the button above, you can download The Binding of Isaac's APK. Duplicated items might not be identical copies of the original - for example duplicating a card may spawn a different card, Jera runes and trinkets cannot be duplicated using the D1, Duplicated chests can turn into another kind of chest randomly (e.g. Each of them deal double your tear damage, similar to how standard blue flies work, War (Red) - Explodes when touching the enemy. * arcade, skull game, black, heart, pink, love, Gives Isaac 2 orbital flies which block enemy shots, Picking up this item as well as 2 other fly-type items will allow you to transform into Lord of the Flies, * item room, treasure room, item room pool, key master pool, key beggar pool, key judgement pool, two, flies, black, When revived, the green mushroom that follows Isaac will disappear and he will respawn with the same amount of red heart containers at full health, Resurrection takes place before all other items which give you an extra life, * secret room pool, mario, green mushroom, extra life, spots, spotted, x1.5 times Damage Multiplier (Does not stack with the multipliers from Cricket's Head / Blood of The Martyr + Book of Belial), Increases the size of your player sprite, but doesn't increase the hitbox, Counts as 1 of 3 mushroom items needed towards the Fun Guy transformation, Counts as 1 of 3 size-increasing items needed towards the Stompy transformation, * boss room pool, boss room item, item room, treasure room, item room pool, red, spots, spotted, amanita muscaria, Enemies touching you take 12 damage, then a poison effect is applied for 6-7 ticks, dealing damage equal to the amount of red hearts you have (up to 30.8 at 12 full red hearts), Has a chance to drop from the Lust miniboss fight, Counts as 1 of 3 syringe items needed towards the Spun transformation. Sales can be randomly applied just like regular shops, The ladder disappears after leaving the starting room, even if you haven't used it yet, In Antibirth this was called Jacob's Ladder, which had to be renamed as Afterbirth+ already had an item with this name, UNLOCK: Unlock this item by defeating Isaac as Jacob & Esau, Permanently shows the location of the boss room on the map, After defeating the shown boss fight, this item will activate a use of the Sun card (full heal and map reveal), fully recharge your active item, remove curses from the floor, gives +3 Damage Up and +1 Luck up for the rest of the floor, Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped), In The Void floor it shows a random boss room, which isn't necessarily Delirium's room, Adds one extra secret room and one extra super secret room to each floor. You may see more or less than this on the Found HUD overlay, however this number varies based on your other damage increasing items. Kicking a frozen enemy will push it into the wall, where it shatters and fires ice shards everywhere (these can then freeze other enemies), Enemies touching the cube while it's not moving or moving slowly will become slowed for a few seconds, and take a small amount of damage, Cube Baby and enemies frozen will block enemy shots, Cube Baby can be launched across the room if you have a melee weapon, Enemies that die now spawn a red ghost, that floats in place of where the enemy died, Activating the item causes all red ghosts in the room to explode, dealing damage to any enemies near them, The explosion doesn't deal damage to Isaac, Damage dealt by each ghost is 3 + 0.04x the HP of the enemy it spawned from, Larger enemies such as minibosses will spawn a larger red ghost that causes 3 explosions, The red ghosts can be moved around slightly by firing tears through them, Using the item will instantly kill any enemy or boss that has the 'ghost' tag and is at 50% or less HP. To help with range, the orbit is now also offset based on the current direction Isaac is shooting, * item room, treasure room, item room pool, grey, gray, asteroid, silver, ball, Creates a friendly blue spider when you kill an enemy, Spiders are spawned at the location where the enemy died, * item room, treasure room, item room pool, pink, smile, E. Coli turns normal enemies into poop if they touch you, Enemies can turn into poop even if they do not do contact damage, allowing you to apply the effect without taking damage, Can be combined with Midas Touch to turn enemies into Golden Poop, This does not work on mini-bosses and bosses. UNLOCK: Unlock this item by defeating Delirium in The Void floor as The Forgotten, A passive item that puts a yellow ring around Isaac. +4 damage from Curved Horn instead of 2, -4 Tear Delay from Cancer instead of 2), Item Pool: Shop, Greed Mode Shop, Mom's Chest, Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. This effect also works on Delirium if it is currently transformed into The Haunt while below half health, UNLOCK: Unlock this item by defeating Greedier mode as Bethany, Identified all pills on pickup, and converts them to their worse counterparts (e.g. by doing a victory lap), UNLOCK: Unlock this item by beating Mom's Heart on Hard Mode with Apollyon, *, grey, gray, brown, orange, steam, coffee, tea, drink, cup, When used, Compost doubles up the current number of blue flies and spiders you have, When picked up, Compost will also destroy every consumable on the ground in the current room and turn each of them into a blue fly or blue spider, If you have no pickups on the ground in the current room and no other flies or spiders, Compost will spawn 1 blue fly or blue spider, When used, this item will distort all the sprites and music, rotating graphics 90 degrees and translating them diagonally up/left, while leaving the hitbox in the same place. ?, Soul of the Lost, 4 rooms: Rune of Ehwaz, Rune of Perthro, Black Rune, Soul of Isaac, Soul of Eve, Soul of Eden, Soul of the Forgotten, Soul of Jacob and Esau, 6 rooms: Rune of Dagaz, Soul of Samson, Soul of Azazel, Soul of Apollyon, Soul of Bethany, 12 rooms: Rune of Jera, Soul of Lilith, Soul of the Keeper, Tears have a chance to fire a fungus tear that sticks to enemies. Clots returning back to Eve deal 3x damage as they suck back in, The type of heart consumed to create a clot will give it different abilities: Soul Hearts = More health, Black Hearts = Dark Matter effect, Eternal Hearts = Sacred Heart effect, Gold Hearts = Midas Touch effect, Bone Hearts = Compound Fracture effect, Rotten Hearts = Less health, Tainted Eve starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: This item comes along with Tainted Eve. He can pick up coins to restore health, Similar to other familiars of this kind, you can hold the drop key to cause him to stand still, If he dies, his corpse turns into a few blue spiders. First ever time beating beast, and completing a list. His body can be controlled and spews blood nearby, Tears fired by the head do a flat 3.5 damage and don't scale, REPENTANCE - Scissors has been redesigned. 's unique poops, Corn poop - Spawns a blue fly every 2 seconds, Flaming poop - Leaves behind fire that damages enemies, Black poop - Creates slowing black creep. with Brimstone you get 4 lasers, Counts as 1 of 3 spider items needed towards the Spider Baby transformation, * item room, treasure room, item room pool, green, black, +2 Damage Up for tears fired from Isaac's left eye, If playing as Cain or you have an item which modifies which eye you fire tears from, each shot has a 50% chance to do +2 Damage, * item room, treasure room, item room pool, poison, green, brown, bottle, jar, danger, Gives Isaac an eye companion that floats around the room and deals 8 damage per tick on contact with enemies, Damage from Isaac's left eye deal roughly +35% damage, * item room, treasure room, item room pool, red, white, When you take damage, this item recharges one room's worth of charge to your spacebar item, For example, with the D6 you would need to take damage 6 times to fully recharge it, * angel room pool, god room pool, angel room item, shop room pool, shop item pool, Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills.