. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. If you have questions about using Injectafer in a child, talk with your doctor. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. In the first group, some people continued taking iron by mouth, while other people took Injectafer. (Hemoglobin is a protein thats found in your red blood cells.). There are currently no generic forms of either drug. Consult the product instructions and your pharmacist for storage details. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Innovators Monograph One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Best food forward: Are algae the future of sustainable nutrition? (See also Notes section.). Can poor sleep impact your weight loss goals? Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Health careproviderscan provide information on how longside effectslast by checking amedication guide. I actually was constipated after my 3rd but didn't think anything of it. Its responsible for carrying oxygen throughout your body. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. A lack of iron can lead to iron deficiency anaemia if left untreated. Back pain. Nose or throat irritation. (And Injectafer is used to treat IDA.) Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). Depending on your anemia symptoms, your weight changes may be different than those described here. What is the latest research on the form of cancer Jimmy Carter has? Below are examples of these side effects. Answer by DrLact: About Venofer usage in lactation. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Phosphorus is an electrolyte that your body needs in order to make energy. These nutrients include iron, vitamin B12, and folate. Always review your medical history with the treatingphysician. It can also cause skin irritation and redness. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y These side effects may include constipation and diarrhea. Last updated on Feb 20, 2023. Venofer is given as an infusion into a vein. Patients with celiac disease (gluten intolerance). ByDr. Side effects like nausea and low blood pressure are common with most iron infusions. There are 2 tests that your doctor will likely You should not receive Venofer if you have known allergies to iron sucrose. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Potential injection site discoloration has happened. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. FG Trade/E+ sia Getty Images However, be sure to take the dosage your doctor prescribes for you. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. And these two doses need to be separated by at least 7 days. Does Venofer Vial interact with other medications? Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. We cancelled my 5th because of the reaction. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Its not known how often people taking a treatment other than Injectafer had diarrhea. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. Iron infusions are given directly into a vein. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. But you kidneys need iron in order to make EPO. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Drug class: Iron products. Last updated August 20, 2020. (A class of medications describes a group of drugs that work in the same way.). It's a more immediate treatment than supplements or dietary changes. Injectafer is a brand-name prescription drug. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Understanding what thoseside effectsare can lead to a strategy to prevent them. Keep all drugs in a safe place. Storage Condition Store in a cool and dry place protected from light. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. The information provided is not intended to replace your healthcare provider's medical advice. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. Sharing this information can help you avoid potential interactions. <> Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. This medication is given by injection into a vein as directed by your doctor. Youll receive doses of either drug by a healthcare professional at a medical facility. No, Injectafer itself wont make you gain weight. wAd**CgI%"nn{Oa[q{r5 Before using, check this product visually for particles or discoloration. Its not known if Injectafer is safe to use during pregnancy. This is not a complete list of side effects and others may occur. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. upper respiratory infection. These people may lose weight as their anemia improves because theyre more active. These lists dont include all possible side effects. With IDA, you have low hemoglobin levels. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. In the US - Call your doctor for medical advice about side effects. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). They can tell you about other medications that may work well for you. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Its possible to get rid of or reduce the severity ofside effects. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. There isnt a known interaction between Injectafer and alcohol. Phosphorus also helps your nerves function properly. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. VenAccess is a trademark of Vifor (International) Inc. Switzerland. Should I avoid certain foods while taking Venofer Vial? Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Is the ketogenic diet right for autoimmune conditions? This website is intended for use by US patients. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. Copyright 1996-2023 Cerner Multum, Inc. Venofer is not for treating other forms of anemia not caused by iron deficiency. I hope you found answers and are feeling better now. These are not all the side effects that may occur; contact your healthcare provider if you have questions. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. (Hemoglobin is a protein thats found in red blood cells.). Here we look at how Injectafer and Venofer are alike and different. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Change in taste. Pain in your limbs. The benefit of treating your condition during pregnancy may outweigh any risks. We comply with the HONcode standard for trustworthy health information. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. Venofer is for use in adults and children at least 2 years old. Back pain. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . Terminal half-life ranges from 7 to 12 hours. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Find out what health conditions may be a health risk when taken with Venofer Vial With IV infusion, the drug is given as a slow drip into your vein over a period of time. It belongs to a class of medications known as iron replacement products. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. This is not a complete list of side effects and others may occur. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. If you have diarrhea while youre taking Injectafer, call your doctor. Tell all of your health care providers that you take Venofer. Properly discard this product when it is expired or no longer needed. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Diarrhea. * Feraheme has a boxed warning for this side effect. Not all possible drug interactions are listed here. This treatment course is split into two doses of the drug, which are given at least 7 days apart. For people with certain medical implants, such as pacemakers, an MRI may pose an . (A medication class describes a group of drugs that work in the same way.). Joint pain. 5 0 obj other treatments you receive, you will need to go back for several treatments with Venofer. reactions at the site of the injection. Dizziness. Theyll likely have you stop taking the pills while youre using Injectafer. Follow all instructions closely. Severeside effectsmay end up causing a lot of disruption in a persons life. I used to get a different type but my . If you have questions about side effects, call your doctor. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. But its not known whether this poses any risk to a child whos breastfed. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. But for other people, doing so could lead to having too much iron in their body. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. (A class of medications describes a group of drugs that work in the same way.). Dizziness. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Injectafer and Feraheme are both brand-name drugs. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Keep all regular medical and laboratory appointments. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Call your doctor for medical advice about side effects. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. A shortage of iron can cause health problems. <> After the infusion, you can drive yourself home and return to your usual activities. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. The Injectafer dosage your doctor prescribes will depend on your body weight. I was surprised too but the Dr said it definitely sounds like a reaction. Your healthcare provider will watch you closely for 30 minutes after each dose. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. Injectafer should be stored between 68F to 77F (20C to 25C). Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Feraheme also comes as a liquid thats given by IV infusion. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. However, many people have no side effects or only have minor side effects. All rights reserved. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Learn about uses, cost, how it works, and more. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Infusions should be administered over at least 15 minutes. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Injectafer isnt available in a generic form. This medication passes into breast milk. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Serious side effects from Injectafer arent common, but they can occur. Tell your doctor about the allergy and what signs you had. Theyll recommend how to manage your condition. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. Before taking Injectafer, talk with your doctor about your health history. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. I can't take oral supplements because they cause horrible debilitating Constipation. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. But you dont necessarily need to eat these foods unless your doctor tells you to do so. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. During pregnancy, this medication should be used only when clearly needed. In the second group, some people switched from taking iron by mouth to taking Injectafer. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. generalized weakness. fever. Keep out of reach of children. HRT, like other medications, does have some side effects and these are thought to be quite common. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. This means you would get two Injectafer doses of 720 mg each. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection.